Kris Posted March 26, 2007 Share Posted March 26, 2007 (edited) Hello from Germany! While searching the net for news about the MDR1-defect I found this forum and was glad to see that this dangerous gene defect is already known. But perhaps here are some new informations. Here in Germany research is going on at the University of Gießen and there have been lectures by the project group. As an owner of a Collie affected by the defect - and having lost another Collie due to a wrong drug - I went to such lectures and informed myself. I had to learn, that Ivermectin is only the tip of the iceberg and that there perhaps is no safe drug for my dog if he gets ill. I also learned that to few people know about this. So, please test your dogs and inform your vets. Then, together with two other women I started to inform people. We created www.mdr1-defekt.de as an information platform to help respectable breeders to consider, among other health aspects, also the “MDR1 defect” as a breeding criterion for amateur breeding. On this sides we provide important informations and show tested dogs - to encourage others to test and to help breeders searching for the right breeding dog. Our hope ist that in the near future no more dogs affected by the defect will be born. This is a great aim for all breeders! We just started last summer not thinking about becoming international. But we became. Up to now we have dogs not only from Germany but also from the Netherlands, Russia or the USA. And now we hope for more Australian Dogs! So again - test your dogs, inform your vets and send us the dates! Thank you for your kind attention! Kris, Germany www.mdr1-defekt.de Edited March 26, 2007 by Kris Link to comment Share on other sites More sharing options...
Erny Posted March 26, 2007 Share Posted March 26, 2007 (edited) Thank you Kris. I am not a breeder, but like to read up on things such as this simply to expand my knowledge. Unfortunately, I don't speak nor understand the German language so am unable to decipher the information on the platform you point to. But welcome to DOL in Australia . Edited March 26, 2007 by Erny Link to comment Share on other sites More sharing options...
Kris Posted March 27, 2007 Author Share Posted March 27, 2007 Hello Erny! Thank you for your welcome! Unfortunately the sides by the University of Gießen are still only in German. So for more informations about the defect you better use the sides of the University of Washington: http://www.vetmed.wsu.edu/depts-VCPL/#Drugs To find a list showing the dangerous drugs please use this link: http://www.busteralert.org/ And because of our german homepage - just scroll down the first page, there you can select a language and will find our mainpages being translated into English and some more languages. We still work nearly every day on our sides. So it was just yesterday when we get th o.k. for publishing an article written by Pat Hutchinson and being published in the International Collie Society Handbook 2004: http://www.mdr1-defekt.de/texte.php?lang=EN&ID=011 On this side you will find links to test laboratories: http://www.mdr1-defekt.de/texte.php?lang=EN&ID=008 Well, I´m sure, the next update will be within the next days. Greetings from Germany, Kris Link to comment Share on other sites More sharing options...
Kris Posted September 11, 2007 Author Share Posted September 11, 2007 Hello from Germany again! Well, we had several updates in the meantime and just welcomed our 500. dog last week! But it still could be more! And there are news about the labs - as we were told, Gribbles Pathology is the only lab licensed to do the test in Australia. Kind regards, Kris www.mdr1-defekt.de Link to comment Share on other sites More sharing options...
InspectorRex Posted September 13, 2007 Share Posted September 13, 2007 Hi Kris A lot of us Aussie Collie owners are already DNA testing our dogs for the Mutant MDR1 gene. I have and mine are Affected. My Vets are very knowledgeable on this topic as I have bomarded them with mountains of information which they keep on their Clinic file. Note if your dog is either Affected or Carrier for Ivermectin Sensitivity they should also not be given non-steriodal anti-inflammatory drugs such as Rimadyl and Metacam. Intersting to note that Akitas, GSD's, Sighthounds also has the MDR1 mutant gene issue but not many in these breeds know about it. another useful site is www.dogsadversereactions.com Link to comment Share on other sites More sharing options...
Kris Posted September 13, 2007 Author Share Posted September 13, 2007 (edited) A lot of us Aussie Collie owners are already DNA testing our dogs for the Mutant MDR1 gene. That are good news. We all should join together to help to get rid of this gene defect. I have and mine are Affected. Lucky dogs. And I confess, I´m jealous because mine is affected and I lost his predecessor due to a wrong drug... But don´t you wan´t to show them on our homepage? My Vets are very knowledgeable on this topic as I have bomarded them with mountains of information which they keep on their Clinic file. *g* We have the same ideas... Note if your dog is either Affected or Carrier for Ivermectin Sensitivity they should also not be given non-steriodal anti-inflammatory drugs such as Rimadyl and Metacam. Well, there is a long list with drug suspected to be dangerous. As one scientist over here in Germany said: For a vet dealing with an affected dog sometimes means to play Rusian roulette. Or, more clearly: There is a great field trial and every affected dogs takes part! Intersting to note that Akitas, GSD's, Sighthounds also has the MDR1 mutant gene issue but not many in these breeds know about it. Akitas, too? That´s new for me! Do you have any source? another useful site iswww.dogsadversereactions.com Thank you! I just bookmarked it! Kind regards, Kris www.mdr1-defekt.de Edited September 13, 2007 by Kris Link to comment Share on other sites More sharing options...
InspectorRex Posted September 14, 2007 Share Posted September 14, 2007 (edited) Hi Kris How do I get my dogs onto your Homepage? my email address is : [email protected] Re the Akitas- was advised of this by a long-standing Akita breeder who is also a Conformation Judge another site www.miniaussierescue.org Edited September 14, 2007 by InspectorRex Link to comment Share on other sites More sharing options...
Kris Posted September 14, 2007 Author Share Posted September 14, 2007 (edited) How do I get my dogs onto your Homepage? You can use our online formular! Mh, I think it´s time to say that I like the Collies downunder very much! Well, about the Akita - up to now I only know that it will be breeds akin to the Collie which maybe affected: Collie, Sheltie, Aussie, Border Collie, Bobtail, White Shepherd (up to now I never heard about a German Shepherd to be affected), Silken Windhound and some other mostly unknown breeds like the German Wäller or the American McNab. I can´t imagine the Akita to be akin with the Collie. So there might be a similar mutation or another drug sensitivity? And did you see that we have linked busteralert.og? From this side I took the idea to make tag for my dog. Kind regards, Kris Edit: Believe it or not - I just had a look at Australian Collie kennels which are listed at dogzonline and stopped at a side where I saw a tricolour Collie very much to my liking. I looked at the pictures, I looked at the pedigrees - and than I looked at the kennel name - Boldfolk! And there really has been a Nauglamir kennel in Australia? Wow... Edited September 14, 2007 by Kris Link to comment Share on other sites More sharing options...
InspectorRex Posted September 15, 2007 Share Posted September 15, 2007 (edited) Thanks Kris for the compliements re my Collies( we are Boldfolk Kennels since 1989), my elderly Dad( whom I care for full-time) think they are beautiful too I will go into the site and add my dogs later Colleen Yes Nauglamir are Registered kennel here we need to exchange email addresses so we can keep in touch. Edited September 15, 2007 by InspectorRex Link to comment Share on other sites More sharing options...
InspectorRex Posted September 15, 2007 Share Posted September 15, 2007 Hi Kris, have added our 2 Collies to the website Link to comment Share on other sites More sharing options...
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