Vaccination Studies, Dr. L Glickmann, Purdue

[Jed]

Obviously, this is in America (Purdue) but it applies to Aus too.

*www.vet.purdue.edu/epi/gdhstudy.htm

<http://www.vet.purdue.edu/epi/gdhstudy.htm>*

*_Purdue_**_University and Hayward Foundation Study on Vaccines_*

For 15 years, some Great Dane breeders have postulated the adverse

effects of the aggressive use of vaccines on the immature (puppy) immune

system. This concern led these breeders to a more conservative approach

to vaccinations, the monitoring of antibody titers before boosters were

given, or in some cases safe alternatives to conventional practice were

invoked.

Over the last two years a cutting edge scientific research study has

been conducted at Purdue University, under the direction of Larry

Glickman, VDM,PhD and his associate Dr. Harm HogenEsch (Curricula Vitae

and the impressive credentials of these scientists are included for your

review). The study proposal is to investigate the autoimmune responses

to vaccines in dogs. This study, at Purdue, was conceptualized by Great

Dane people, and subsequently funded (± $175,000.00) by a Great Dane

friendly organization called the John & Winifred Hayward Foundation.

Originally, it was considered ideal to conduct the study with a colony

of Great Danes. However, the feasibility and practicality of

maintaining and housing a controlled group of Great Danes was

economically out of reach. Therefore, the study identified the Beagle as

the canine of choice, but recognized the applications of any results to

the canine population as a whole, including Great Danes.

The study has produced some dramatic results, with concrete and clear

evidence that there are adverse events elicited as a result of the use

of vaccines following manufacturer's recommendations. (Review the

following article for a more complete picture of study results.)

In Dr. LaRosa's (Trustee of the Hayward Foundation) article (following),

he states that a number of autoantibodies to several critical proteins

and DNA were identified in the vaccinated group. Identifying these

autoimmune antibodies, and monitoring their titers may lead, in addition

to the thyroiditis conditions, a better understanding of the role of

vaccines in soliciting adverse events that contribute to problematic

conditions observed in the Great Dane, such as Cardiomyopathy, and

Various Bone related disorders.

The positive outcomes of the study at Purdue will hopefully be the

identification of a number of genetic markers that will facilitate a

brighter and healthier future for our breed, as well as recommendations

for safer vaccines and their uses.

The Hayward Foundation is limited by its charter to investigate Human

Genetic Disorders, therefore its ability to significantly fund this

study further falls outside of the realm of its charter. However, the

Trustees of the Hayward Foundation have committed an additional

$25,000.00 to help in the maintenance of this colony until further

funding is identified.

Glickman has stated that the colony will be lost unless further and

immediate funding is identified to maintain the colony . Dr. Glickman

is applying to the AKC Foundation and the NIH (National Institute of

Health) for funding. Two years of research will not be lost but the

future of this work which relies on maintaining the colony for some time

to come will be lost.

[shortstep]

Obviously, this is in America (Purdue) but it applies to Aus too.

*www.vet.purdue.edu/epi/gdhstudy.htm

<http://www.vet.purdue.edu/epi/gdhstudy.htm>*

*_Purdue_**_University and Hayward Foundation Study on Vaccines_*

For 15 years, some Great Dane breeders have postulated the adverse

effects of the aggressive use of vaccines on the immature (puppy) immune

system. This concern led these breeders to a more conservative approach

to vaccinations, the monitoring of antibody titers before boosters were

given, or in some cases safe alternatives to conventional practice were

invoked.

Over the last two years a cutting edge scientific research study has

been conducted at Purdue University, under the direction of Larry

Glickman, VDM,PhD and his associate Dr. Harm HogenEsch (Curricula Vitae

and the impressive credentials of these scientists are included for your

review). The study proposal is to investigate the autoimmune responses

to vaccines in dogs. This study, at Purdue, was conceptualized by Great

Dane people, and subsequently funded (± $175,000.00) by a Great Dane

friendly organization called the John & Winifred Hayward Foundation.

Originally, it was considered ideal to conduct the study with a colony

of Great Danes. However, the feasibility and practicality of

maintaining and housing a controlled group of Great Danes was

economically out of reach. Therefore, the study identified the Beagle as

the canine of choice, but recognized the applications of any results to

the canine population as a whole, including Great Danes.

The study has produced some dramatic results, with concrete and clear

evidence that there are adverse events elicited as a result of the use

of vaccines following manufacturer's recommendations. (Review the

following article for a more complete picture of study results.)

In Dr. LaRosa's (Trustee of the Hayward Foundation) article (following),

he states that a number of autoantibodies to several critical proteins

and DNA were identified in the vaccinated group. Identifying these

autoimmune antibodies, and monitoring their titers may lead, in addition

to the thyroiditis conditions, a better understanding of the role of

vaccines in soliciting adverse events that contribute to problematic

conditions observed in the Great Dane, such as Cardiomyopathy, and

Various Bone related disorders.

The positive outcomes of the study at Purdue will hopefully be the

identification of a number of genetic markers that will facilitate a

brighter and healthier future for our breed, as well as recommendations

for safer vaccines and their uses.

The Hayward Foundation is limited by its charter to investigate Human

Genetic Disorders, therefore its ability to significantly fund this

study further falls outside of the realm of its charter. However, the

Trustees of the Hayward Foundation have committed an additional

$25,000.00 to help in the maintenance of this colony until further

funding is identified.

Glickman has stated that the colony will be lost unless further and

immediate funding is identified to maintain the colony . Dr. Glickman

is applying to the AKC Foundation and the NIH (National Institute of

Health) for funding. Two years of research will not be lost but the

future of this work which relies on maintaining the colony for some time

to come will be lost.

I tried both links but cannot get either to work, it is just me??

[stormie]

Here's a link that has the full study... thought it would be more recent than it is, but still very interesting!

http://vonhapsburg.homestead.com/haywardstudyonvaccines.html

this is very interesting!

To date, routing vaccination of these Beagles has not caused any overt signs of clinical disease. However, the blood of all the vaccinated dogs contains significantly elevated concentrations of antibodies directed against proteins that are present in commercial vaccines as contaminants of the production process. None of the unvaccinated control dogs has had a similar increase in these antibodies. These proteins are typically of bovine origin since fetal calf serum is used to grow the viruses for vaccine production. The close similarity in structure of the bovine proteins to dog proteins results in a situation whereby the antibodies produced by the vaccinated dogs may cross-react with dog tissue proteins in a process similar to autoimmunity

. Edited March 14, 2011 by stormie

[sandgrubber]

It's a progress report from 1999! I'd expect a lot has been learned since then. What I got out of the report was that someone really wanted to keep their study dogs going (understandable). They had gotten some interesting results that suggest things and may support the hypothesis they were testing (unfortunate. . . I would much rather see someone trying to falsify the hypothesis).

The anti-vaccine crowd has come in for a lot of debunking in the US lately with widespread acknowledgement that the results supposedly linking autism to vaccination were cooked, invalid, and unable to be replicated . . . causing great waste of money and resulting in many kids getting infectious diseases cause their parents had been scared off vaccines.