Tay. Posted September 7, 2009 Share Posted September 7, 2009 What exactly is TNS? Link to comment Share on other sites More sharing options...
MolassesLass Posted September 7, 2009 Share Posted September 7, 2009 TNS stands for Trapped Neutrophil Syndrome, an hereditary disease where the bone marrow produces neutrophils (white cells) but is unable to effectively release them into the bloodstream. Affected puppies have an impaired immune system and will eventually die from infections they cannot fight. More Info Link to comment Share on other sites More sharing options...
Tay. Posted September 7, 2009 Author Share Posted September 7, 2009 Thanks ^^ Link to comment Share on other sites More sharing options...
dancinbcs Posted September 7, 2009 Share Posted September 7, 2009 The info link is from before the test was developed. We have now had a DNA test available at the Uni of NSW for about 4 years and all Border Collies need to have their genetic status determined before breeding. TNS is found in ALL bloodlines, including working lines all around the world. As TNS is inherited as an autosomal recessive condition both parents need to carry it for puppies to be affected. Therefore, so long as one parent of each litter is DNA normal, the puppies cannot suffer from TNS. If both parents are DNA normal then all the puppies will automatically be normal as well and will not require testing. Puppies from a mating with one carrier parent only need to be tested to determine if they are carriers, when and if they are to be used for breeding. Border Collies also need to have their DNA status determined for CL and CEA before breeding and the same breeding guidelines as TNS apply for each of these conditions. All reputable breeders have now been DNA testing for 3 or 4 years and it is really only the puppy farmers and those breeding just for the pet market that will have untested stock. There will shortly be an ANKC breed survey out for breeders/ owners to decide about mandatory testing before litters are registered. Having these tests available means that there should not be any more Border Collies born suffering from any of these hereditary diseases. As other hereditary problems are extremely rare the breed is now one of the healthiest available. Link to comment Share on other sites More sharing options...
Tay. Posted September 8, 2009 Author Share Posted September 8, 2009 Thanks dancinbcs That makes a lot more sense lol. Link to comment Share on other sites More sharing options...
grabonsam Posted September 10, 2009 Share Posted September 10, 2009 Does anybody know how much TNS testing costs if one parent is a carrier? Link to comment Share on other sites More sharing options...
piper Posted September 10, 2009 Share Posted September 10, 2009 Does anybody know how much TNS testing costs if one parent is a carrier? This is from a fact sheet about the testing" Cost of testing for TNS is $88 AUD. CL testing can be done on the same sample for a further $55 AUD. Link to comment Share on other sites More sharing options...
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