Thanks for your replies.
My vet did blood tests and Millie has cholestasis and she had a major infection which my previous vet picked up but when she went to our new vet it was only now minor. My vet has printed me up all information about cholestasis. He has told me I can put her onto Milk Thistle and is on a strict diet of Hills Prescrition, she loves the biccies but not keen on the tinned food.
http://www.petmd.com/dog/conditions/digestive/c_dg_bile_duct_obstruction