I have used everything known to man. I recently moved into a new house & all my dogs ended up with fleas. I had a litter of pups & they all ended up with fleas as well. I used frontline spray but still the fleas remained. I also treated bedding, yard, house & even the car. When I took my pups to the vet for their vaccinations the vet actually took pics to give to the frontline rep as my pups were still covered in fleas. The vet suggested I use Fidos shampoo, a capstar tablet & I also gave them a Sentinel tablet. With my adults dogs I have found that advantage works much better than frontline. Thank heavens we are now flea free again!!!